Mono-Acetone Glucose

Name: Acetone Glucose, Acetone-D-Glucose, 1,2-O-Isopropylidene-α-D-glucofuranose, 1,2-O-Isopropylidene-alpha-D-glucofuranose, Monoacetone Glucofuranose，1,2-O-(1-methylethylidene)- α-D-glucofuranose.

Molecular formula:  C₉H₁₆O₆

Molecular weight:  220.22

CAS#：18549-40-1

Molecular structure:

Specification:

Characteristics:

White crystalline solid. Dissolve in water, acetone, ethanol, tetrahydrofuran，dimethyl formamide etc.

Uses: 

This product is an important pharmaceutical intermediates. Used in synthesis nojirimycin and deoxynojirimycin for treatment diabetes, complexes that carbohydrate combine with organic metal including platinum, osmium tetroxide, ruthenium, etc for treatment cancer, other anticancer or antitumor pharmaceuticals and their precursor such as organic phosphide, and azole that contain glycosyl for resistance to junin virus and fever virus such as dengue fever, dengue hemorrhagic fever and Argentine hemorrhagic fever. In addition, the derivatives of 1,2-O-isopropylidene-α-D-glucofuranose, for example, that the 3-O-position or 6-O-position is substituted by N'methylpiperidyl, N', N'-dimethylaminoethyl, N', N'-diethylaminoethyl, N', N -3 trimethylaminoethyl-n-propyl, N' N 'dimethylaminopropyl and so on, are the ideal antibiotic medicine substitute, which used in therapy diseases of immune system, such as rheumatoid arthritis, rheumatic fever, eczema, lupus erythematosus, etc. The derivatives that 3-O-position is substituted by one or more than one of the different groups or 3,5,6-O-position all is substituted, are used in treating of the following diseases, such as cardiovascular disease, bronchial asthma, rheumatoid arthritis, multiple sclerosis, allograft rejection, psoriasis, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, pruritis and allergic rhinitis. The derivatives that 3-O-position is acetylized is used in preparation of medicament for therapy of hematological diseases associated with a failure in the expression of β-globin genes. N-substitute butyramide derivatives of 1,2-O-isopropylidene-α-D-glucofuranose is a kind of enkephalinase inhibitors, which used in treating alzheimer's disease, etc. The researches that using 1,2-O-isopropylidene-α-D-glucofuranose to tailor glycopeptide provide theoretical guidance for treatment disease and development of new immune pharmaceuticals.

Used in synthesis molecular tweezers of glucose based water soluble.

Used in synthesis carrier, release carrier of pharmaceutical and the diagnostic reagents.

The derivatives that 3-O-position is substituted by benzyl group, which is a raw material for preparation pesticide.

Used in synthesis derivatives of tagatose.

Used in synthesis acrylic ester.

Used in preparation colorant stablizer or light-stabilized dyestuff, which impart light stability to the colorant so that the colorant does not fade when exposed to electromagnetic radiation such as sunlight or artificial light.

Used in preparation polymerization catalysts.

Used in synthesis emulsifier of 6-O-palmitoyl-1,2-O-isopropylidene-α-D-glucofuranose.

Used in synthesis [18F]-6-deoxy-6-fluoro-D-glucose, which is a tracer of glucose transport and is applied to positron emission tomography (PET) in medicine area.

Storage: 

Store in a tightly closed container. Maintain in a cool and dry area.

Package:  

25kg/drum or as required by customer.

Expiration Date: 2 years.